||Bioinformatician, The Jenner Institute, University of Oxford, UK
||Bioinformatics Consultant, Zurich, Switzerland
||Research Fellow in Bioinformatics, IMCB, Singapore
||PhD, ETH, Zurich, Institute of Cell Biology. Thesis: Transcriptional dynamics in immune cells at hypoxic conditions.
||Diploma in Biology, Karls-Ruprecht University, Heidelberg, Major Biochemistry/Biophysics. Thesis: mRNA stability and degradation.
||Linux, Cluster handling (PBS server), Windows
||Daily use during work: R, Python, MySQL
||Frequent use: Linux Tools (awk, sed …) , C
||Past projects: Matlab, Java, Perl, C++, VBA-Excel
|Publications (up to date list)|
|Salvany L, Muller J, Guccione E, and Rorth P.
The core and conserved role of MAL is homeostatic regulation of actin levels.
Genes & Development, May 15, 2014; 28 (10)
|Loh SL, Teh C, Muller J, Guccione E, Hong W and Korzh V.
Zebrafish yap1 plays a role in differentiation of hair cells in posterior lateral line.
Science Reports, Mar 6, 2014; 4:4289
|Jachowicz J, Santenard A, Bender A, Muller J and Torres-Padilla ME.
Heterochromatin establishment at pericentromeres depends on nuclear position.
Genes & Development, Nov 15, 2013; 27(22):2427-32
|Wang X*, Zhao Z*, Muller J, Iyu A, Khng AJ, Guccione E, Ruan Y, and Ingham PW. * Equally contributing
Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish.
Biology Open, Nov 15, 2013; 2(11):1203-13
|Burton A*, Muller J*, Padilla-Longoria P, Guccione E and Torres-Padilla ME. * Equally contributing
Single-Cell Profiling of Epigenetic Modifiers Identifies PRDM14 as an Inducer of Cell Fate in the Mammalian Embryo.
Cell Reports, Nov 14, 2013; 5(3):687-701 (Video Featured Article)
|Filipponi D, Muller J, Emelyanov A and Bulavin DV.
Wip1 Controls Global Heterochromatin Silencing via ATM/BRCA1-Dependent DNA Methylation.
Cancer Cell, Oct 14, 2013; 24(4):528-41 (Featured Article)
|Windak R, Muller J, Felley A, Akhmedov A, Wagner EF, Pedrazzini T, Sumara G, and Ricci R.
The AP-1 Transcription Factor c-Jun Prevents Stress-Imposed Maladaptive Remodeling of the Heart.
PLoS One, Sep 10, 2013; 8(9)
|Bezzi M, Teo SX, Muller J, Mok WC, Sahu SK, Vardy LA, Bonday ZQ and Guccione E.
Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.
Genes & Development, Sep 1, 2013; 27(17):1903-16
|Bard-Chapeau EA, Gunaratne J, Kumar P, Chua B, Muller J, Bard FA, Blackstock W, Copeland NG, and Jenkins NA.
EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.
PNAS, Jul 30, 2013; 110(31):2885-94
|Kumpf S, Mihlan M, Goginashvili A, Grandl G, Gehart H, Godel A, Schmidt J, Muller J, Bezzi M, Ittner A, Guccione E, Wolfrum C, Ricci R.
Hairless promotes PPARγ expression and is required for white adipogenesis
EMBO Reports, Nov 6, 2012; 13(11):1012-20
|Bard-Chapeau EA, Jeyakani J, Kok CH, Muller J, Chua B, Gunaratne J, Batagov A, Jenjaroenpun P, Kuznetsov VA, Wei CL, D'Andrea R, Bourque G, Jenkins NA and Copeland NG.
Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors
PNAS, Feb 7, 2012; 109(6):2168-73
|Migliori V, Muller J, Low D, Phalke S, Bezzi M, Gunaratne J, Mok WC, Capasso P, Bassi C, Cecatiello V, Kuznetsov V, Blackstock W, Amati B, Mapelli M and Guccione E.
Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance
Nature Structural & Molecular Biology, Jan 8, 2012; 19(2):136-44 (Cover Article)
|Järve A, Muller J, Kim IH, Rohr K, MacLean C, Fricker G, Massing U, Eberle F, Dalpke A, Fischer R, Trendelenburg MF and Helm M.
Surveillance of siRNA integrity by FRET imaging
Nucleic Acids Research, Sep 22, 2007; 35(18)
|Kurschat WC, Muller J, Wombacher R and Helm M.
Optimizing splinted ligation of highly structured small RNAs
RNA, Oct 26, 2005; 11(12):1909-14